Endocrine Abstracts

We describe the case of a 39-year-old lady who was diagnosed with acromegaly in 1997 with basal GH 89.9 mu/l with paradoxical rise to 152 mu/l on OGTT, her IGF-1 was 76 nmol/l refrange (9.5–45). She underwent transphenoidal hypophysectomy in 1998 for pituitary microadenoma and postoperatively her growth hormone level was 5 mu/l. Six months following surgery she had an OGTT during which she suppressed her growth hormone levels to a nadir of 5 mu/l and her IGF-1 was 46.1 nm...

We present the case of a Caucasian girl who in 1991 at the age of 4 started virilising and was diagnosed to have 21-hydroxylase deficiency. She started her periods at 10 and has been under regular follow up. In 2004 she underwent vaginoplasty and clitoral reduction and made good recovery. She has been stable on hydrocortisone 10 mg in the morning, 12.5 mg in the evening and fludrocortisone 50 mcg once daily (Testosterone<0.7 mmol/l (0.5–3.0), 17-hydroxy progesterone=1...

We present the case of a 32-year-old gentleman who was initially referred to the urologists with erectile dysfunction, low libido and infertility. There was no history of headache, visual difficulty, galactorrhea and his smell sensation was fine. Blood tests done in February 2007 showed normal renal, liver and thyroid function. His Prolactin was elevated at 3086 mU/l, with no detectable macroprolactin. He had hypogonadotrophic hypogonadism (testosterone=1.8 nmol/l (10–40)...